Symposium



Quad


2016 Scheduled Lecture Synopsis

01 Mar 2016 12:41 PM | Lauren Renaud (Administrator)

Erica Watson
Behavioral Management in an R&D Environment
Synopsis:
Implementing a behavioral management program or trying to standardize existing socialization, enrichment and housing programs can be very challenging in the research environment.  Constrained budgets, limited time to implement/evaluate and document strategies, scientific constraints and a never-ending supply of great ideas can quickly dilute the focus and effectiveness of even the most well-intentioned behavioral management program.  In this session we will review the steps taken, including some project management tactics, at GlaxoSmithKline to 1) review, improve and standardize existing behavioral management strategies 2) develop a process for on-boarding, approval, implementation and evaluation of future strategies and 3) develop worldwide behavioral performance standards.

Krystal Allen-Worthington, DVM, PhD
Raise a glass: verification of intraperitoneal ethanol as a humane method of euthanasia for laboratory mice
Synopsis:

We sought to evaluate intraperitoneal (IP) ethanol injection as a method of euthanasia by using ECG and high-definition video recording. Mice (n = 85) and rats (n = 16) were treated with IP ethanol (70% or 100%), pentobarbital–phenytoin combination (Pe/Ph), or saline. After injection, animals were assessed for behavioral and physiologic responses. Pain-assessment techniques in mice demonstrated that intraperitoneal injection of ethanol was not more painful than was intraperitoneal Pe/Ph. Median time to loss of consciousness for all mice that received ethanol or Pe/Ph was 45 sec. For mice, IP injection of ethanol induced rapid and irreversible loss of consciousness, followed by death, and should be considered as “acceptable with conditions.”

Bober, Ramona
NASA Animal Care and Use
Synopsis:
Animals have flown into space dating back to the year 1783 when the Montgolfier brothers sent a sheep, a duck, and a rooster aloft in a hot air balloon.
NASA was created in 1958 and endeavors involving animals date back to 1961 with the Mercury Redstone rockets launched from Cape Canaveral Air force Station and continue into present day with animals residing on the International Space Station.
This talk will provide a history of animals in space and an overview of the spaceflights that have been supported over the years

Philip Gerwin, DVM, MS
Ecto-and Ectoparasite Detection in Laboratory Mice: Past, Present, and Future
Synopsis:
Murine parasites remain a concern for any vivarium housing rodents for research. Therefore, the laboratory animal professional must have an in-depth understanding of the common endoparasites and ectoparasites of laboratory mice. The prevalence, morphology, life cycle, effects on health and research, diagnostic tests, and exclusion strategies will be reviewed with an emphasis on comparing traditional and contemporary detection methods.  As PCR testing has become the prevailing contemporary test method for quarantine and health monitoring programs, the role of PCR testing in modern vivaria will be discussed, using data from recent and soon to be published studies.

Robert Quinn, DVM
Euthanasia: Why it is different when we talk about people?
Synopsis:
The world views euthanasia of animals differently than euthanasia of people.  Why?
We will review the various meanings of euthanasia as applied in both veterinary and human medicine and we will compare and contrast the ethical views about euthanasia as it relates to both animals and people. Finally, we will examine how these views are changing as our society changes.

Jennifer Kylie DVM
Factors Affecting the Rabbit Fecal Microbiota
Synopsis:
Studies have demonstrated the importance of maintaining a healthy gastrointestinal microbiota in both health and behaviour in animals. As rabbits are routinely used in a variety of study types in research, it is incredibly important to gain an understanding of the typical microbiota of rabbit in order to understand how various factors may alter its composition, resulting in changes in health and behaviour status, which, ultimately, may influence research results. The current study aims to examine the fecal microbiota of a variety of rabbit populations coming from several different sources with differences in age, season, and antimicrobial use status. We have been able to demonstrate that the majority of these factors do significantly affect the microbiota composition, which, in turn, may affect research results. These results raise several interesting points with respect to the impact that the rabbit fecal microbiota may have on the predisposition to disease development, as well as reproducibility of results and model phenotypes in rabbit-based research.

James 'Robbie' Champion
It’s Time to Speak Up. Pro-Test!
Synopsis:
My presentation is regarding speaking up about research.  In a world filled with inaccurate representations of research, it is time we as an industry speak up.  Tell the world what we do.  By being more open in research, we can regain some trust in society.  By making it personal, we can affect change in how the general population feels about how research is managed.  By putting a human face and humane reasons behind what we do, we may connect with the general population so that truly understand what it takes to provide medical care and treatment for human and animal diseases.

Kathleen Pritchett-Corning
Why mice have always mattered

Synopsis:
Mice have lived in close proximity to humans since before the dawn of agriculture and our relationship with them reflects the messy complexities of commensalism.  Humans have exterminated, venerated, domesticated, and experimented on mice while also managing to introduce them to new habitats around the world.  Similarly, mice occupy a complicated niche in our relationship with animals since they may be vermin, competing with humans for food; valued pets, living in captive luxury; research subjects, advancing knowledge to contribute to human health; or (rarely) appreciated linchpins of ecosystems. From where did the mouse come and where is it headed?
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